University of California San Francisco

Elaine Tseng Headshot large
Elaine
Tseng
MD, FACS, FAHA

Professor of Surgery
Division of Cardiothoracic Surgery
Chief of Cardiac Surgery, San Francisco VA Healthcare System
Co-Director, Cardiac Biomechanics Lab

UCSF Diversity, Equity, and Inclusion Champion badge

Academic Address
500 Parnassus Avenue, W405, Box 0118
San Francisco, CA 94143
Tel: (415) 353-8890
Email: [email protected] 
Assistant: [email protected] 

San Francisco VA Medical Center
4150 Clement St, (112)
San Francisco, CA 94121
Tel: (415) 221-4810
 

Biography

Dr. Elaine Tseng is Professor of Surgery in the Division of Cardiothoracic Surgery at University of California San Francisco Medical Center. Her clinical expertise includes minimally invasive aortic valve replacement with Y-root enlargement, Ross operation, aortic surgery including ascending thoracic aortic aneurysm repairs, valve sparing aortic root replacements, structural heart disease—transcatheter aortic valve replacement and transcatheter edge-to-edge repair, and multi-arterial coronary artery bypass grafting.

Dr. Tseng grew up in North Carolina where she attended the North Carolina School of Science and Mathematics. She was a National Merit Scholar. She completed her undergraduate Bachelor of Science at the Massachusetts Institute of Technology where she graduated Phi Beta Kappa with a GPA 5.0. She earned her medical degree at Harvard Medical School and was one of three recipients per year of the Virginia A. Linnane Scholarship. Dr. Tseng underwent her general surgery training at The Johns Hopkins Hospital, where she received the George D. Zeidema Surgery Award and the Vincent L. Gott Cardiac Surgery Award. She was inducted into the Alpha Omega Alpha Honor Society and was awarded the Nina Braunwald Research Fellowship Award from The Thoracic Surgery Foundation for Research and Education. She also received the Hawley H. Seiler MD Award from the Southern Thoracic Surgical Association. Dr. Tseng underwent her clinical and advanced training in cardiothoracic surgery at The Johns Hopkins Hospital.

After completing her education and training, she joined the cardiac surgery staff at the UCSF and SFVA Medical Centers in 2002. Her academic research interests over the past 20 years have involved biomechanics, fluid dynamics, and computational simulations of aortic root surgery, including aortic stenosis, transcatheter aortic valves, Ross operation, ascending thoracic aortic aneurysm (aTAA) and dissection. She has been NIH R01 funded surgeon-scientist investigating the biomechanics of ascending thoracic aortic aneurysms to determine better predictors of type A dissection than maximum diameter. She is currently funded through a VA Merit award to investigate the impact of aTAA biomechanics on dissection, rupture, and all-cause mortality. She is the UCSF/SFVA site-principal investigator for the multi-institutional international randomized trial of treatment of ascending thoracic aortic aneurysms, TITAN trial, early surgery vs surveillance for 5.0-5.4cm aneurysms. She has published >100 scientific papers and book chapters. Dr. Tseng serves on the Society of Thoracic Surgeons (STS) Workforce on New Technology, American Association for Thoracic Surgery (AATS) Clinical Practice Standards Committee. She is on the Board of Directors of the Heart Valve Society, and the Thoracic Surgery Foundation. She is the Vice-Chair of the Cardiovascular Surgery and Anesthesia Council of the American Heart Association and is Senior Editor in the Editorial Board of Annals of Thoracic Surgery. She is a fellow of the American College of Surgeons and the American Heart Association and is certified by the American Board of Surgery and the American Board of Thoracic Surgery.

Education

Institution Degree Dept or School End Date
University of California Diversity, Equity, and Inclusion Champion Training 2018
Lenox Hill Hospital Fellowship Endovascular/Interventional Cardiology 2006
Johns Hopkins Hospital Fellowship Cardiac Surgery 2000
Johns Hopkins Hospital Research Fellowship Cardiac Surgery 1997
Johns Hopkins Hospital Residency General Surgery 1995
Johns Hopkins Hospital Internship General Surgery 1994
Harvard Medical School M.D. Health Sciences and Technology (HST) Division 1993
Massachusetts Institute of Technology B.S. 1989

Board Certifications

American Board of Surgery, 2000

American Board of Thoracic Surgery, 2003

Clinical Expertise

Acute and chronic type B aortic dissections
Aortic arch aneurysms
Aortic valve surgery
Ascending aortic and arch surgery
Endovascular repair of descending thoracic aortic aneurysm
Hypothermic circulatory arrest (HCA)
Marfan syndrome
Maze procedure for atrial fibrillation
Maze procedure for atrial fibrillation
Minimally invasive valve surgery
Off-pump coronary artery bypass
Reoperative cardiac surgery
Robotic cardiac surgery

Clinical Trials

  1. Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance (NCT03536312)
    Related Conditions: Aneurysm| Start Date: | End Date:

Grants and Funding

  • Developing Biomechanical Predictors of Ascending Thoracic Aortic Aneurysm Growth and Dissection | Veteran Affairs | 2022-04-01 - 2026-04-01 | Role: Principal Investigator
  • Development of a System to Remove and Replace Transcatheter Heart Valves Percutaneously | Veterans Affairs | 2023-04-01 - 2024-03-31 | Role: Principal Investigator
  • Improved Rupture Risk Assessment of Ascending Thoracic Aortic Aneurysms: Application of Patient-specific Modeling and Biomechanics | Marfan Fundation | 2020-02-15 - 2023-06-30 | Role: Principal Investigator
  • Biomechanical Understanding of Ascending Thoracic Aortic Aneurysms | NIH | 2015-04-01 - 2021-03-31 | Role: Principal Investigator

Research Interests

Percutaneous and transcatheter aortic valves
Biomechanics
Computational fluid dynamics
Valvular heart diseases

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 150
  1. In Vivo Quantification of Ascending Thoracic Aortic Aneurysm Wall Stretch Using MRI: Relationship to Repair Threshold Diameter and Ex Vivo Wall Failure Behavior.
    Dong H, Haraldsson H, Leach J, Zhou A, Ballweber M, Zhu C, Xuan Y, Wang Z, Hope M, Epstein FH, Ge L, Saloner D, Tseng E, Mitsouras D| | PubMed
  2. Saphenous Vein Graft Pseudoaneurysm Treated With Covered Stenting.
    Patel JN, Anderson DR, Ghauri MS, Yang J, Zimmet J, Tseng E, Shunk KA, Boskovski M| | PubMed
  3. Temporal evolution of ascending aortic aneurysm wall stress predicts all-cause mortality.
    Zamirpour S, Gulati A, Xuan Y, Leach JR, Saloner DA, Guccione JM, Boskovski MT, Ge L, Tseng EE| | PubMed
  4. Evaluating the safety and efficacy of a novel polysaccharide hemostatic system during surgery: A multicenter multispecialty prospective randomized controlled trial.
    House MG, Kim R, Tseng EE, Kaufman RP, Moon MR, Yopp A, Master VA| | PubMed
  5. Impact of nondiameter aortic indices on surgical eligibility: Results from the Treatment in Thoracic Aortic Aneurysm: Surgery Versus Surveillance (TITAN: SvS) randomized controlled trial.
    Dagher O, Appoo JJ, Herget E, Atoui R, Baeza C, Brinkman W, Bozinovski J, Chu MWA, Dagenais F, Demers P, Desai N, El-Hamamsy I, Estrera A, Grau JB, Hughes GC, Jassar A, Kachroo P, Lachapelle K, Ouzounian M, Patel HJ, Pozeg Z, Tseng E, Whitlock R, Guo MH, Boodhwani M| | PubMed
  6. Minimally invasive aortic valve replacement with Y-incision aortic root enlargement.
    Boskovski MT, Arammash M, Nguyen TC, Tseng EE| | PubMed
  7. Height and body surface area versus wall stress for stratification of mid-term outcomes in ascending aortic aneurysm.
    Zamirpour S, Xuan Y, Wang Z, Gomez A, Leach JR, Mitsouras D, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  8. Reimplantation vs Remodeling: End of the Debate?
    Tseng EE, Boskovski M| | PubMed
  9. Impact of Oral Anticoagulation on Clinical Outcomes in Postoperative Atrial Fibrillation.
    Almassi GH, Quin JA, Stock EM, DeMatt EJ, Biswas K, Hattler B, Tseng E, Zenati MA| | PubMed
  10. Sex differences in ascending aortic size reporting and growth on chest computed tomography and magnetic resonance imaging.
    Zamirpour S, Boskovski MT, Pirruccello JP, Pace WA, Hubbard AE, Leach JR, Ge L, Tseng EE| | PubMed
  11. Navigating Promotion in Thoracic Surgery.
    Boskovski MT, Tseng EE| | PubMed
  12. Ascending thoracic aortic aneurysm size at presentation and growth by diameter.
    Pace WA, Smith K, Gamboa A, Zamirpour S, Ge L, Tseng E| | PubMed
  13. Perspectives on the 2022 joint guidelines on the diagnosis and management of aortic disease.
    Hui DS, Chen EP, DeAnda A, Girardi LN, Kim KM, Woo YJ, Tseng EE, Preventza O| | PubMed
  14. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.
    Writing Committee Members, Isselbacher EM, Preventza O, Hamilton Black J, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A, Fanola CL, Girardi LN, Hicks CW, Hui DS, Schuyler Jones W, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Ross EG, Schermerhorn ML, Singleton Times S, Tseng EE, Wang GJ, Woo YJ, Peer Review Committee Members, Faxon DP, Upchurch GR, Aday AW, Azizzadeh A, Boisen M, Hawkins B, Kramer CM, Luc JGY, MacGillivray TE, Malaisrie SC, Osteen K, Patel HJ, Patel PJ, Popescu WM, Rodriguez E, Sorber R, Tsao PS, Santos Volgman A, AHA/ACC Joint Committee Members, Beckman JA, Otto CM, O'Gara PT, Armbruster A, Birtcher KK, de Las Fuentes L, Deswal A, Dixon DL, Gorenek B, Haynes N, Hernandez AF, Joglar JA, Jones WS, Mark D, Mukherjee D, Palaniappan L, Piano MR, Rab T, Spatz ES, Tamis-Holland JE, Woo YJ| | PubMed
  15. Aortic area/height ratio, peak wall stresses, and outcomes in veterans with tricuspid versus bicuspid aortic valve-associated ascending thoracic aortic aneurysms.
    Zamirpour S, Xuan Y, Wang Z, Gomez A, Leach J, Mitsouras D, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  16. Ascending thoracic aortic aneurysm elongation occurs in parallel with dilatation in a nonsurgical population.
    Gulati A, Zamirpour S, Leach J, Khan A, Wang Z, Xuan Y, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  17. Formal consensus study on surgery to replace the aortic valve in adults aged 18-60 years.
    Stoica S, Beard C, Takkenberg JJM, Mokhles MM, Turner M, Pepper J, Hopewell-Kelly N, Benedetto U, Nashef SAM, El-Hamamsy I, Skillington P, Glauber M, De Paulis R, Tseng E, Meuris B, Sitges M, Delgado V, Krane M, Kostolny M, Pufulete M| | PubMed
  18. Regional and directional delamination properties of healthy human ascending aorta and sinotubular junction.
    Xuan Y, Wang Z, Guccione JM, Tseng EE, Ge L| | PubMed
  19. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.
    Isselbacher EM, Preventza O, Hamilton Black J, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A, Fanola CL, Girardi LN, Hicks CW, Hui DS, Schuyler Jones W, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Gyang Ross E, Schermerhorn ML, Singleton Times S, Tseng EE, Wang GJ, Woo YJ, Peer Review Committee Members| | PubMed
  20. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.
    Writing Committee Members, Isselbacher EM, Preventza O, Hamilton Black Iii J, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A, Fanola CL, Girardi LN, Hicks CW, Hui DS, Jones WS, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Ross EG, Schermerhorn ML, Times SS, Tseng EE, Wang GJ, Woo YJ| | PubMed
  21. Midterm Durability and Structural Valve Degeneration of Transcatheter Aortic Valve Replacement in a Federal Facility.
    Yang R, Grober AF, Riojas R, Ponna V, Shunk KA, Zimmet JM, Gustafson J, Ge L, Tseng EE| | PubMed
  22. Proximal Aortic Surgery in Women-We Need to Do Better.
    Tseng EE| | PubMed
  23. Association of 3-Year All-Cause Mortality and Peak Wall Stresses of Ascending Thoracic Aortic Aneurysms in Veterans.
    Zamirpour S, Xuan Y, Wang Z, Gomez A, Hope MD, Leach J, Mitsouras D, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  24. Regional wall stress differences on tricuspid aortic valve-associated ascending aortic aneurysms.
    Gomez A, Wang Z, Xuan Y, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  25. Eptifibatide bridging therapy for staged carotid artery stenting and cardiac surgery: Safety and feasibility.
    Caton MT, Narsinh KH, Baker A, Amans MR, Hetts SW, Rapp JH, Ianuzzi JC, Tseng E, Gasper WJ, Cooke DL| | PubMed
  26. Under Pressure-To See or Not To See.
    Tseng EE| | PubMed
  27. Ascending thoracic aortic aneurysm growth is minimal at sizes that do not meet criteria for surgical repair.
    Gulati A, Leach J, Wang Z, Xuan Y, Hope MD, Saloner DA, Ge L, Tseng EE| | PubMed
  28. Restrictive versus liberal transfusion in patients with diabetes undergoing cardiac surgery: An open-label, randomized, blinded outcome evaluation trial.
    Mistry N, Shehata N, Carmona P, Bolliger D, Hu R, Carrier FM, Alphonsus CS, Tseng EE, Royse AG, Royse C, Filipescu D, Mehta C, Saha T, Villar JC, Gregory AJ, Wijeysundera DN, Thorpe KE, Jüni P, Hare GMT, Ko DT, Verma S, Mazer CD, TRICS Investigators| | PubMed
  29. Time to Remove the Left Atrial Appendage at Surgery: LAAOS III in Perspective.
    Verma S, Bhatt DL, Tseng EE| | PubMed
  30. Wall stresses of early remodeled pulmonary autografts.
    Xuan Y, Alonso E, Emmott A, Wang Z, Kumar S, Mongeon FP, Leask RL, El-Hamamsy I, Ge L, Tseng EE| | PubMed
  31. Patient-Specific Biomechanics in Marfan Ascending Thoracic Aortic Aneurysms.
    Xuan Y, D'Souza SN, Wang Z, Pierre AS, Lawton JS, Ge L, Tseng EE| | PubMed
  32. Regional biomechanical and failure properties of healthy human ascending aorta and root.
    Xuan Y, Wisneski AD, Wang Z, Lum M, Kumar S, Pallone J, Flores N, Inman J, Lai L, Lin J, Guccione JM, Tseng EE, Ge L| | PubMed
  33. Discussion.
    Tseng EE| | PubMed
  34. Minimally invasive surgical aortic valve replacement in setting of pseudoxanthoma elasticum.
    Anderson D, Gustafson J, Tseng EE| | PubMed
  35. Association of diameter and wall stresses of tricuspid aortic valve ascending thoracic aortic aneurysms.
    Gomez A, Wang Z, Xuan Y, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  36. Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.
    Freeman-Cook KD, Hoffman RL, Behenna DC, Boras B, Carelli J, Diehl W, Ferre RA, He YA, Hui A, Huang B, Huser N, Jones R, Kephart SE, Lapek J, McTigue M, Miller N, Murray BW, Nagata A, Nguyen L, Niessen S, Ninkovic S, O'Doherty I, Ornelas MA, Solowiej J, Sutton SC, Tran K, Tseng E, Visswanathan R, Xu M, Zehnder L, Zhang Q, Zhang C, Dann S| | PubMed
  37. Development of the Minimalist Approach for Transcatheter Aortic Valve Replacement at a Veterans Affairs Medical Center.
    Lum MY, Wang SX, Wisneski AD, Liang NE, Zimmet J, Shunk KA, Stechert M, London MJ, Ge L, Tseng EE| | PubMed
  38. Impact of Transcatheter Aortic Valve Size on Leaflet Stresses: Implications for Durability and Optimal Grey Zone Sizing.
    Xuan Y, Dvir D, Wisneski AD, Wang Z, Ye J, Guccione JM, Ge L, Tseng EE| | PubMed
  39. Commentary: Virtual thoracic endovascular aortic repair for type A aortic dissection: Engineering transforms clinical reality.
    Wang Z, Xuan Y, Tseng EE, Ge L| | PubMed
  40. Long-term outcomes after transcatheter aortic valve implantation in failed bioprosthetic valves.
    Bleiziffer S, Simonato M, Webb JG, Rodés-Cabau J, Pibarot P, Kornowski R, Windecker S, Erlebach M, Duncan A, Seiffert M, Unbehaun A, Frerker C, Conzelmann L, Wijeysundera H, Kim WK, Montorfano M, Latib A, Tchetche D, Allali A, Abdel-Wahab M, Orvin K, Stortecky S, Nissen H, Holzamer A, Urena M, Testa L, Agrifoglio M, Whisenant B, Sathananthan J, Napodano M, Landi A, Fiorina C, Zittermann A, Veulemans V, Sinning JM, Saia F, Brecker S, Presbitero P, De Backer O, Søndergaard L, Bruschi G, Franco LN, Petronio AS, Barbanti M, Cerillo A, Spargias K, Schofer J, Cohen M, Muñoz-Garcia A, Finkelstein A, Adam M, Serra V, Teles RC, Champagnac D, Iadanza A, Chodor P, Eggebrecht H, Welsh R, Caixeta A, Salizzoni S, Dager A, Auffret V, Cheema A, Ubben T, Ancona M, Rudolph T, Gummert J, Tseng E, Noble S, Bunc M, Roberts D, Kass M, Gupta A, Leon MB, Dvir D| | PubMed
  41. Reply from authors: Aortic aneurysm biomechanics: Perfect is the enemy of good.
    Tseng EE, Wang Z, Ge L| | PubMed
  42. Stent and leaflet stresses across generations of balloon-expandable transcatheter aortic valves.
    Xuan Y, Dvir D, Wang Z, Ye J, Guccione JM, Ge L, Tseng EE| | PubMed
  43. Wall Stress Distribution in Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysms.
    Gomez A, Wang Z, Xuan Y, Wisneski AD, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  44. Wall stress analyses in patients with ≥5 cm versus <5 cm ascending thoracic aortic aneurysm.
    Wang Z, Flores N, Lum M, Wisneski AD, Xuan Y, Inman J, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE| | PubMed
  45. Outcomes of Veterans Undergoing TAVR Within Veterans Affairs Medical Centers: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program.
    Hall PS, O'Donnell CI, Mathew V, Garcia S, Bavry AA, Banerjee S, Jneid H, Denktas AE, Giacomini JC, Grossman PM, Aggarwal K, Zimmet JM, Tseng EE, Gozdecki L, Burke L, Bertog SC, Buchbinder M, Plomondon ME, Waldo SW, Shunk KA| | PubMed
  46. Veterans Affairs Heart Team Experience With Transcatheter Aortic Valve Replacement and Minimally Invasive Surgical Aortic Valve Replacement.
    Liang NE, Wisneski AD, Wang SX, Shunk KA, Wozniak CJ, Yang J, Zimmet JM, Ge L, Tseng EE| | PubMed
  47. Evolution of Minimally Invasive Surgical Aortic Valve Replacement at a Veterans Affairs Medical Center.
    Liang NE, Wisneski AD, Wozniak CJ, Ge L, Tseng EE| | PubMed
  48. Evolution of Bilateral Mammary Arterial Grafting Program in Veterans Affairs Medical Center.
    Wang SX, Lee M, Chang CC, Lai LYY, Flores N, Ge L, Wozniak CJ, Tseng EE| | PubMed
  49. Range of Pulmonary Autograft Responses to Systemic Pressure Immediately After Ross Procedure.
    Wisneski AD, Wang Z, Xuan Y, Guccione JM, Ge L, Tseng EE| | PubMed
  50. Randomized Trial of Endoscopic or Open Vein-Graft Harvesting for Coronary-Artery Bypass.
    Zenati MA, Bhatt DL, Bakaeen FG, Stock EM, Biswas K, Gaziano JM, Kelly RF, Tseng EE, Bitondo J, Quin JA, Almassi GH, Haime M, Hattler B, DeMatt E, Scrymgeour A, Huang GD, REGROUP Trial Investigators| | PubMed
  51. Factors associated with early dropout in an employer-based commercial weight-loss program.
    Alexander E, Tseng E, Durkin N, Jerome GJ, Dalcin A, Appel LJ, Clark JM, Gudzune KA| | PubMed
  52. Long-term retention in an employer-based, commercial weight-loss programme.
    Alexander E, Tseng E, Durkin N, Jerome GJ, Dalcin A, Appel LJ, Clark JM, Gudzune KA| | PubMed
  53. Stent and leaflet stresses in 26-mm, third-generation, balloon-expandable transcatheter aortic valve.
    Xuan Y, Dvir D, Wang Z, Mizoguchi T, Ye J, Guccione JM, Ge L, Tseng EE| | PubMed
  54. Wall stress on ascending thoracic aortic aneurysms with bicuspid compared with tricuspid aortic valve.
    Xuan Y, Wang Z, Liu R, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng E| | PubMed
  55. Evolution of Veterans Affairs Transcatheter Aortic Valve Replacement Program: The First 100 Patients.
    Yang J, Zimmet JM, Ponna VM, Ma F, Wozniak CJ, Ge L, Shunk KA, Tseng EE| | PubMed
  56. Impact of Patient-Specific Material Properties on Aneurysm Wall Stress: Finite Element Study.
    Wang Z, Xuan Y, Guccione JM, Tseng EE, Ge L| | PubMed
  57. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast.
    Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, Saloner D, Hope MD| | PubMed
  58. Stent and Leaflet Stresses in 29-mm Second-Generation Balloon-Expandable Transcatheter Aortic Valve.
    Xuan Y, Krishnan K, Ye J, Dvir D, Guccione JM, Ge L, Tseng EE| | PubMed
  59. Leaflet Mechanical Properties of Carpentier-Edwards Perimount Magna Pericardial Aortic Bioprostheses.
    Kuang H, Xuan Y, Lu M, Mookhoek A, Wisneski AD, Guccione JM, Ge L, Tseng EE| | PubMed
  60. Ferumoxytol MRA for transcatheter aortic valve replacement planning with renal insufficiency.
    Kallianos K, Henry TS, Yeghiazarians Y, Zimmet J, Shunk KA, Tseng EE, Mahadevan V, Hope MD| | PubMed
  61. Stent and leaflet stresses in a 26-mm first-generation balloon-expandable transcatheter aortic valve.
    Xuan Y, Krishnan K, Ye J, Dvir D, Guccione JM, Ge L, Tseng EE| | PubMed
  62. Biomechanics of Failed Pulmonary Autografts Compared to Native Aortic Roots.
    Mookhoek A, Krishnan K, Chitsaz S, Kuang H, Ge L, Schoof PH, Bogers AJJC, Takkenberg JJM, Tseng EE| | PubMed
  63. In vitro evaluation of implantation depth in valve-in-valve using different transcatheter heart valves.
    Simonato M, Azadani AN, Webb J, Leipsic J, Kornowski R, Vahanian A, Wood D, Piazza N, Kodali S, Ye J, Whisenant B, Gaia D, Aziz M, Pasala T, Mehilli J, Wijeysundera HC, Tchetche D, Moat N, Teles R, Petronio AS, Hildick-Smith D, Landes U, Windecker S, Arbel Y, Mendiz O, Makkar R, Tseng E, Dvir D| | PubMed
  64. Biomechanics of Failed Pulmonary Autografts Compared With Normal Pulmonary Roots.
    Mookhoek A, Krishnan K, Chitsaz S, Kuang H, Ge L, Schoof PH, Bogers AJ, Takkenberg JJ, Tseng EE| | PubMed
  65. Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model.
    Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE| | PubMed
  66. Vascular Operations Performed by Cardiothoracic Surgeons: The Society of Thoracic Surgeons Survey.
    Ikonomidis JS, Ad N, Aldea GS, Argenziano M, Galloway AC, Hagberg RC, Kormos RL, Lawton JS, Mihaljevic T, Reece TB, Tseng EE| | PubMed
  67. When valve-in-valve implantation is not sufficient: Bioprosthetic Russian dolls.
    Tseng EE| | PubMed
  68. Flow-Induced Damage to Blood Cells in Aortic Valve Stenosis.
    Vahidkhah K, Cordasco D, Abbasi M, Ge L, Tseng E, Bagchi P, Azadani AN| | PubMed
  69. Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
    Cheng H, Nair SK, Murray BW, Almaden C, Bailey S, Baxi S, Behenna D, Cho-Schultz S, Dalvie D, Dinh DM, Edwards MP, Feng JL, Ferre RA, Gajiwala KS, Hemkens MD, Jackson-Fisher A, Jalaie M, Johnson TO, Kania RS, Kephart S, Lafontaine J, Lunney B, Liu KK, Liu Z, Matthews J, Nagata A, Niessen S, Ornelas MA, Orr ST, Pairish M, Planken S, Ren S, Richter D, Ryan K, Sach N, Shen H, Smeal T, Solowiej J, Sutton S, Tran K, Tseng E, Vernier W, Walls M, Wang S, Weinrich SL, Xin S, Xu H, Yin MJ, Zientek M, Zhou R, Kath JC| | PubMed
  70. Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysm: Patient-Specific Finite Element Analysis.
    Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE| | PubMed
  71. In Vitro Kinetic Characterization of Axitinib Metabolism.
    Zientek MA, Goosen TC, Tseng E, Lin J, Bauman JN, Walker GS, Kang P, Jiang Y, Freiwald S, Neul D, Smith BJ| | PubMed
  72. Proof of concept of FOLDAVALVE, a novel 14 Fr totally repositionable and retrievable transcatheter aortic valve.
    Kheradvar A, Groves EM, Tseng E| | PubMed
  73. Ascending thoracic aortic aneurysm wall stress analysis using patient-specific finite element modeling of in vivo magnetic resonance imaging.
    Krishnan K, Ge L, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Tseng EE| | PubMed
  74. Development of a Veterans Affairs hybrid operating room for transcatheter aortic valve replacement in the cardiac catheterization laboratory.
    Shunk KA, Zimmet J, Cason B, Speiser B, Tseng EE| | PubMed
  75. Extended 3D approach for quantification of abnormal ascending aortic flow.
    Sigovan M, Dyverfeldt P, Wrenn J, Tseng EE, Saloner D, Hope MD| | PubMed
  76. Patient-specific finite element analysis of ascending thoracic aortic aneurysm.
    Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE| | PubMed
  77. Successful percutaneous management of partial avulsion of the native aortic valve complex complicating transcatheter aortic valve replacement.
    Zimmet J, Kaiser E, Tseng E, Shunk K| | PubMed
  78. Systolic flow displacement correlates with future ascending aortic growth in patients with bicuspid aortic valves undergoing magnetic resonance surveillance.
    Burris NS, Sigovan M, Knauer HA, Tseng EE, Saloner D, Hope MD| | PubMed
  79. Human pulmonary autograft wall stress at systemic pressures prior to remodeling after the Ross procedure.
    Wisneski AD, Matthews PB, Azadani AN, Mookhoek A, Chitsaz S, Guccione JM, Ge L, Tseng EE| | PubMed
  80. Feasibility of asymmetric stretch assessment in the ascending aortic wall with DENSE cardiovascular magnetic resonance.
    Haraldsson H, Hope M, Acevedo-Bolton G, Tseng E, Zhong X, Epstein FH, Ge L, Saloner D| | PubMed
  81. Invited commentary.
    Ge L, Tseng EE| | PubMed
  82. Biomechanical properties of human ascending thoracic aortic aneurysms.
    Azadani AN, Chitsaz S, Mannion A, Mookhoek A, Wisneski A, Guccione JM, Hope MD, Ge L, Tseng EE| | PubMed
  83. Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart.
    Wenk JF, Ge L, Zhang Z, Mojsejenko D, Potter DD, Tseng EE, Guccione JM, Ratcliffe MB| | PubMed
  84. Magnetic resonance measurement of turbulent kinetic energy for the estimation of irreversible pressure loss in aortic stenosis.
    Dyverfeldt P, Hope MD, Tseng EE, Saloner D| | PubMed
  85. Identification of multiple 5-HT₄ partial agonist clinical candidates for the treatment of Alzheimer's disease.
    Brodney MA, Johnson DE, Sawant-Basak A, Coffman KJ, Drummond EM, Hudson EL, Fisher KE, Noguchi H, Waizumi N, McDowell LL, Papanikolaou A, Pettersen BA, Schmidt AW, Tseng E, Stutzman-Engwall K, Rubitski DM, Vanase-Frawley MA, Grimwood S| | PubMed
  86. Improved preclinical cardiovascular therapeutic indices with long-term inhibition of norepinephrine reuptake using reboxetine.
    Fossa AA, Wisialowski TA, Cremers T, van der Hart M, Tseng E, Deng S, Rollema H, Wang EQ| | PubMed
  87. Material properties of CorCap passive cardiac support device.
    Chitsaz S, Wenk JF, Ge L, Wisneski A, Mookhoek A, Ratcliffe MB, Guccione JM, Tseng EE| | PubMed
  88. Imaging biomarkers of aortic disease: increased growth rates with eccentric systolic flow.
    Hope MD, Wrenn J, Sigovan M, Foster E, Tseng EE, Saloner D| | PubMed
  89. Acute type A aortic dissection intimal tears by 64-slice computed tomography: a role for endovascular stent-grafting?
    Jaussaud N, Chitsaz S, Meadows A, Wintermark M, Cambronero N, Azadani AN, Saloner DA, Chuter TA, Tseng EE| | PubMed
  90. Hemodynamic determinants of aortic dissection propagation by 2D computational modeling: implications for endovascular stent-grafting.
    Chitsaz S, Azadani AN, Matthews PB, Chuter TA, Tseng EE, Ge L| | PubMed
  91. Regional mechanical properties of human pulmonary root used for the Ross operation.
    Azadani AN, Chitsaz S, Matthews PB, Jaussaud N, Leung J, Ge L, Tseng EE| | PubMed
  92. Cerebrospinal fluid amyloid-β (Aβ) as an effect biomarker for brain Aβ lowering verified by quantitative preclinical analyses.
    Lu Y, Riddell D, Hajos-Korcsok E, Bales K, Wood KM, Nolan CE, Robshaw AE, Zhang L, Leung L, Becker SL, Tseng E, Barricklow J, Miller EH, Osgood S, O'Neill BT, Brodney MA, Johnson DS, Pettersson M| | PubMed
  93. Correlation of calcification on excised aortic valves by micro-computed tomography with severity of aortic stenosis.
    Chitsaz S, Gundiah N, Blackshear C, Tegegn N, Yan KS, Azadani AN, Hope M, Tseng EE| | PubMed
  94. Patient-specific multiscale modeling of blood flow for coronary artery bypass graft surgery.
    Sankaran S, Esmaily Moghadam M, Kahn AM, Tseng EE, Guccione JM, Marsden AL| | PubMed
  95. The 5-hydroxytryptamine4 receptor agonists prucalopride and PRX-03140 increase acetylcholine and histamine levels in the rat prefrontal cortex and the power of stimulated hippocampal θ oscillations.
    Johnson DE, Drummond E, Grimwood S, Sawant-Basak A, Miller E, Tseng E, McDowell LL, Vanase-Frawley MA, Fisher KE, Rubitski DM, Stutzman-Engwall KJ, Nelson RT, Horner WE, Gorczyca RR, Hajos M, Siok CJ| | PubMed
  96. First evidence of depressed contractility in the border zone of a human myocardial infarction.
    Wenk JF, Klepach D, Lee LC, Zhang Z, Ge L, Tseng EE, Martin A, Kozerke S, Gorman JH, Gorman RC, Guccione JM| | PubMed
  97. A coupled biventricular finite element and lumped-parameter circulatory system model of heart failure.
    Wenk JF, Ge L, Zhang Z, Soleimani M, Potter DD, Wallace AW, Tseng E, Ratcliffe MB, Guccione JM| | PubMed
  98. Biomechanical comparison of human pulmonary and aortic roots.
    Azadani AN, Chitsaz S, Matthews PB, Jaussaud N, Leung J, Wisneski A, Ge L, Tseng EE| | PubMed
  99. Transcatheter heart valves for failing bioprostheses: state-of-the-art review of valve-in-valve implantation.
    Azadani AN, Tseng EE| | PubMed
  100. Incidental aortic valve calcification on CT scans: significance for bicuspid and tricuspid valve disease.
    Hope MD, Urbania TH, Yu JP, Chitsaz S, Tseng E| | PubMed
  101. Echo rounds: aneurysm of the anterior mitral valve.
    Stechert MM, Pletcher JR, Tseng EE, London MJ| | PubMed
  102. Comparison of mechanical properties of human ascending aorta and aortic sinuses.
    Azadani AN, Chitsaz S, Matthews PB, Jaussaud N, Leung J, Tsinman T, Ge L, Tseng EE| | PubMed
  103. Post-stenotic dilation: evaluation of ascending aortic dilation with 4D flow MR imaging.
    Hope MD, Dyverfeldt P, Acevedo-Bolton G, Wrenn J, Foster E, Tseng E, Saloner D| | PubMed
  104. Operative risks and survival in veterans with severe aortic stenosis: surgery versus medical therapy.
    Chitsaz S, Jaussaud N, Chau E, Yan KS, Azadani AN, Ratcliffe MB, Tseng EE| | PubMed
  105. Valve-in-valve hemodynamics of 20-mm transcatheter aortic valves in small bioprostheses.
    Azadani AN, Jaussaud N, Ge L, Chitsaz S, Chuter TA, Tseng EE| | PubMed
  106. Finite element modeling of the pulmonary autograft at systemic pressure before remodeling.
    Matthews PB, Jhun CS, Yaung S, Azadani AN, Guccione JM, Ge L, Tseng EE| | PubMed
  107. Closure of aortic paravalvular leak under intravascular ultrasound and intracardiac echocardiography guidance.
    Sharma M, Tseng E, Schiller N, Moore P, Shunk KA| | PubMed
  108. Transcatheter valve-in-valve implantation for failing bioprosthetic valves.
    Azadani AN, Tseng EE| | PubMed
  109. Live transference of surgical subspecialty skills using telerobotic proctoring to remote general surgeons.
    Ereso AQ, Garcia P, Tseng E, Gauger G, Kim H, Dua MM, Victorino GP, Guy TS| | PubMed
  110. Comparison of porcine pulmonary and aortic root material properties.
    Matthews PB, Azadani AN, Jhun CS, Ge L, Guy TS, Guccione JM, Tseng EE| | PubMed
  111. Transcatheter aortic valves inadequately relieve stenosis in small degenerated bioprostheses.
    Azadani AN, Jaussaud N, Matthews PB, Ge L, Chuter TA, Tseng EE| | PubMed
  112. Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest.
    Tseng EE, Brock MV, Lange MS, Troncoso JC, Blue ME, Lowenstein CJ, Johnston MV, Baumgartner WA| | PubMed
  113. Energy loss due to paravalvular leak with transcatheter aortic valve implantation.
    Azadani AN, Jaussaud N, Matthews PB, Ge L, Guy TS, Chuter TA, Tseng EE| | PubMed
  114. Valve-in-valve implantation using a novel supravalvular transcatheter aortic valve: proof of concept.
    Azadani AN, Jaussaud N, Matthews PB, Ge L, Guy TS, Chuter TA, Tseng EE| | PubMed
  115. A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysm.
    Sun K, Stander N, Jhun CS, Zhang Z, Suzuki T, Wang GY, Saeed M, Wallace AW, Tseng EE, Baker AJ, Saloner D, Einstein DR, Ratcliffe MB, Guccione JM| | PubMed
  116. Biomechanical perspective on the porcine pulmonary root prior to Ross remodeling.
    Matthews PB, Kim B, Azadani AN, Guy TS, Guccione JM, Ge L, Tseng EE| | PubMed
  117. Migration forces of transcatheter aortic valves in patients with noncalcific aortic insufficiency.
    Dwyer HA, Matthews PB, Azadani A, Ge L, Guy TS, Tseng EE| | PubMed
  118. Aortic valve-in-valve implantation: impact of transcatheter- bioprosthesis size mismatch.
    Azadani AN, Jaussaud N, Matthews PB, Chuter TA, Ge L, Guy TS, Guccione J, Tseng EE| | PubMed
  119. Usability of robotic platforms for remote surgical teleproctoring.
    Ereso AQ, Garcia P, Tseng E, Dua MM, Victorino GP, Guy LT| | PubMed
  120. Computational fluid dynamics simulation of transcatheter aortic valve degeneration.
    Dwyer HA, Matthews PB, Azadani A, Jaussaud N, Ge L, Guy TS, Tseng EE| | PubMed
  121. Mechanical properties of surgical glues used in aortic root replacement.
    Azadani AN, Matthews PB, Ge L, Shen Y, Jhun CS, Guy TS, Tseng EE| | PubMed
  122. Retrograde cerebral perfusion and delayed hyperbaric oxygen for massive air embolism during cardiac surgery.
    Guy TS, Kelly MP, Cason B, Tseng E| | PubMed
  123. Significant material property differences between the porcine ascending aorta and aortic sinuses.
    Gundiah N, Matthews PB, Karimi R, Azadani A, Guccione J, Guy TS, Saloner D, Tseng EE| | PubMed
  124. Robotic mammary artery harvest and anastomotic device allows minimally invasive mitral valve repair and coronary bypass.
    Guy TS, Brzezinski M, Stechert MM, Tseng E| | PubMed
  125. A simple correction for anomalous coronary arteries in adults.
    Guy TS, Tseng E, Ratcliffe MB, Azakie A, Karl TR| | PubMed
  126. Robotic cardiac surgery: give it more time!
    Guy TS, Tseng E| | PubMed
  127. Invited commentary.
    Tseng E, Matthews PB, Guy TS| | PubMed
  128. Asymmetric mechanical properties of porcine aortic sinuses.
    Gundiah N, Kam K, Matthews PB, Guccione J, Dwyer HA, Saloner D, Chuter TA, Guy TS, Ratcliffe MB, Tseng EE| | PubMed
  129. Central nervous system pharmacokinetics of the Mdr1 P-glycoprotein substrate CP-615,003: intersite differences and implications for human receptor occupancy projections from cerebrospinal fluid exposures.
    Venkatakrishnan K, Tseng E, Nelson FR, Rollema H, French JL, Kaplan IV, Horner WE, Gibbs MA| | PubMed
  130. Percutaneous technique for creation of tricuspid regurgitation in an ovine model.
    Hoppe H, Pavcnik D, Chuter TA, Tseng E, Kim MD, Bernat I, Uchida B, Keller FS, Rösch J| | PubMed
  131. Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia.
    Mann MJ, Tseng E, Ratcliffe M, Strattman G, De Silva A, Demarco T, Achorn N, Moskalik W, Hoopes C| | PubMed
  132. Reversal of direct thrombin inhibition after cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia.
    Stratmann G, deSilva AM, Tseng EE, Hambleton J, Balea M, Romo AJ, Mann MJ, Achorn NL, Moskalik WF, Hoopes CW| | PubMed
  133. Profound hypoxemia resulting from shunting across an inadvertent atrial septal tear after left ventricular assist device placement.
    Baker JE, Stratmann G, Hoopes C, Donateillo R, Tseng E, Russell IA| | PubMed
  134. Barrett's esophagus with high grade dysplasia: surgical results and long-term outcome--an update.
    Tseng EE, Wu TT, Yeo CJ, Heitmiller RF| | PubMed
  135. Cerebral hemodynamics changes during retrograde brain perfusion in dogs.
    Razumovsky AY, Tseng EE, Hanley DF, Baumgartner WA| | PubMed
  136. Training women surgeons and their academic advancement.
    Baumgartner WA, Tseng EE, DeAngelis CD| | PubMed
  137. Laparoscopic nephrectomy for autotransplantation.
    Fabrizio MD, Kavoussi LR, Jackman S, Chan DY, Tseng E, Ratner LE| | PubMed
  138. Prevalence of aspiration and laryngeal penetration in patients with unilateral vocal fold motion impairment.
    Heitmiller RF, Tseng E, Jones B| | PubMed
  139. Apoptosis detection in brain using low-magnification dark-field microscopy.
    Lange MS, Johnston MV, Tseng EE, Baumgartner WA, Blue ME| | PubMed
  140. Assessing the impact of cerebral injury after cardiac surgery: will determining the mechanism reduce this injury?
    Baumgartner WA, Walinsky PL, Salazar JD, Tseng EE, Brock MV, Doty JR, Redmond JM, Blue ME, Goldsborough MA, Troncoso JC, Johnston MV| | PubMed
  141. Increased intracerebral excitatory amino acids and nitric oxide after hypothermic circulatory arrest.
    Tseng EE, Brock MV, Kwon CC, Annanata M, Lange MS, Troncoso JC, Johnston MV, Baumgartner WA| | PubMed
  142. Nitric oxide mediates neurologic injury after hypothermic circulatory arrest.
    Tseng EE, Brock MV, Lange MS, Troncoso JC, Lowenstein CJ, Blue ME, Johnston MV, Baumgartner WA| | PubMed
  143. Relationship of the long thoracic nerve to the scapular tip: an aid to prevention of proximal nerve injury.
    Salazar JD, Doty JR, Tseng EE, Marin PC, Girotto JA, Roseborough GS, Yang SC, Heitmiller RF| | PubMed
  144. Monosialoganglioside GM1 inhibits neurotoxicity after hypothermic circulatory arrest.
    Tseng EE, Brock MV, Lange MS, Troncoso JC, Blue ME, Lowenstein CJ, Johnston MV, Baumgartner WA| | PubMed
  145. The role of the monosialoganglioside, GM1 as a neuroprotectant in an experimental model of cardiopulmonary bypass and hypothermic circulatory arrest.
    Baumgartner WA, Redmond JM, Zehr KJ, Brock MV, Tseng EE, Blue ME, Troncoso JC, Johnston MV| | PubMed
  146. Neuronal nitric oxide synthase inhibition reduces neuronal apoptosis after hypothermic circulatory arrest.
    Tseng EE, Brock MV, Lange MS, Blue ME, Troncoso JC, Kwon CC, Lowenstein CJ, Johnston MV, Baumgartner WA| | PubMed
  147. Aortic valve replacement in the elderly. Risk factors and long-term results.
    Tseng EE, Lee CA, Cameron DE, Stuart RS, Greene PS, Sussman MS, Watkins L, Gardner TJ, Baumgartner WA| | PubMed
  148. Selective endothelial dysfunction in conscious dogs after cardiopulmonary bypass.
    Zanaboni P, Murray PA, Simon BA, Zehr K, Fleischer K, Tseng E, Nyhan DP| | PubMed
  149. Pathophysiology of cerebral injury and future management.
    Baumgartner WA, Redmond M, Brock M, Tseng E, Blue ME, Troncoso JC, Johnston MV| | PubMed
  150. Overcoming rejection in pig-to-primate cardiac xenotransplantation.
    Davis EA, Jakobs F, Pruitt SK, Greene PS, Qian Z, Lam TT, Tseng E, Levin JL, Baldwin WM, Sanfilippo F| | PubMed